Polio Virus History And Recent Outbreaks
Introduction Poliomyelitis is an infectious disease caused by poliovirus, a positive-sense RNA enterovirus in the family Picornaviridae. Most infections produce no symptoms, but a small proportion invade the nervous system and can cause irreversible flaccid paralysis or death. The original essay correctly explains fecal–oral transmission, viral replication, the inactivated and oral vaccines, and the history of Salk and Sabin. It is outdated in listing India and Nigeria as endemic, understates

