HMG-CoA Reductase Inhibitors Functions and Side Effects
HMG-CoA reductase inhibitors are a class of drugs that are used to lower lipids. They work by inhibiting the action of the Enzyme HMG-CoA reductase, which plays a central role in the manufacturing and production of cholesterol in the human body. HMG-CoA reductase inhibitors include Pitavastatin, Rosuvastatin, lovastatin, Fluvastatin, and Simvastatin (Goldstein and Michael 163). These medications are often referred to as Statins. They are used to reduce the amount