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Nanofabricated Neural Probes for Dense 3D Recordings of Brain Activity


“Nanofabricated Neural Probes for Dense 3 D Recordings of Brain Activity” is an article which was written by Athanassios G. Siapas, Michael L. Roukes, Derrick Chi, Evgueniy V. Lubenov, and Gustavo Rios and published by the American Chemical Society in 2016. The purpose of the article was to develop a dense Three-Dimensional (3-D) electrode array to be used for electrophysiology. According to the writers, this is a configurable system architecture that specializes in monitoring neural activity. The benefit of this innovation is that it operates using an unprecedented resolution and scale.

The writer begins their analysis by presenting a detailed and precise recap of the steps that have been taken and accomplishments realized so far in the functionality of the brain. According to their research, much is already known about brain response properties such as memory rise, learning, motor control, and perception. However, little research has been conducted to understand much about the circuit interactions of individual brain cells. This happens because scientists have found it challenging to measure the activities of the neurons, especially in human beings and other behaving animals (Schwarz et al. 2014). This has resulted in the use of electrophysiology as the most effective alternative for monitoring the brain. However, the authors refute the effectiveness of electrophysiology because of its invasiveness in the recording of the spatial resolution, spatial extent, and electrodes. Since this issue remains unresolved, the researchers came up with an innovative idea whose implementation, they believe, would help provide an ultimate solution to the computation challenges (Xie et al., 2013). The configurable system and the front-end molecular architecture-mounted 3-D electrode arrays for electrophysiology will seek to address that.

After keenly reading the article and understanding every bit of it, I would like to point out that it is indeed a well-written piece. The authors did a commendable job because, during the entire time I read the article, I realized that it is of the highest possible standard. The writers used an appropriate structure composed of the abstract, background information, research, findings, and conclusion. In the abstract, a precise but critical review of the whole article was done. Here, the researchers summarized all the main points covered in the article. In the introduction, the authors provide comprehensive background information on the research efforts and the pending issues that must be addressed through such innovative work. For instance, they explain all the major milestones and the loopholes that still need to be filled through further research. After giving such insightful background information, the writers discuss, in detail, everything about the new technology. All the points made are supported using real evidence and made sensible using graphic illustrations (Khodagholy, et al. 2013). The authors explain all the necessary information about the technology and how it can be used to ensure it accomplishes its objectives. At the same time, the article includes enough information on all the features and properties of the innovation.

In conclusion, “Nanofabricated Neural Probes for Dense 3 D Recordings of Brain Activity” is an insightful article that presents research that the scholars carried out to address a real-life problem. It is an excellent article that contains adequate textual and graphic information on the subject matter. Despite researching such a complex topic, the writers tried all they could to simplify the language and make it easier for anyone who reads the article to understand. If the article is implemented, its recommendations and findings can significantly contribute to accurately recording all brain activities.



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