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Medical Case Study

Patient Information

Introductory Summary

Patient A is a 55-year-old Hispanic female with a chief complaint of having swollen legs. She is currently taking Chlorthalidone 50 mg for the management of her swollen legs and Pravastatin 80 mg for high cholesterol. She has a blood pressure of 149/95 and a pulse rate of 69 bpm. Her respiratory rate is 14, and her body temperature is 36.6oC. She does not have any allergy to any drug or food substance. She also complains of having had drowsiness, nausea, fatigue, headache, and feeling lightheaded over the past week.

Medical Conditions

The patient has the following medical conditions: High blood pressure, pitting oedema, headache, and high blood cholesterol.


To the cardiologist: please provide detailed information about this patient, including venous return and electrocardiogram.

To the pharmacist: Kindly provide detailed information on pravastatin and chlorthalidone that the patient currently uses, including comprehensive information on the interactions of each drug with other drugs, food or chemicals, and side effects of each drug.

To the Nephrologist: Please assess the current state of the patient’s renal system and determine whether Chlorthalidone 50 mg has effectively managed her condition.

To the laboratory: measure the patient’s blood cholesterol levels, including HDL and LDL.

The response from the pharmacist indicates that chlorthalidone has side effects such as dizziness, nausea, fatigue, lightheadedness, and drowsiness. The drug also causes erratic blood glucose levels, low potassium, and high levels of calcium ions (Chobanian, p96). The headache that the patient complained about could be a result of the drug. The pharmacist advised that the patient could be put on spironolactone, a potassium-sparing diuretic. The laboratory report indicated that the LDL levels were still very high. Hence, the patient needs to continue using pravastatin.

Treatment Summary

The patient shall continue using pravastatin for her high cholesterol levels. To alleviate dizziness and headache, the patient shall terminate Chlorthalidone 50 mg and instead be put on spironolactone.

Discussion of Medical Conditions

The rationale for changing diuretics is that Chlorthalidone presents with several side effects, such as low potassium, headache, drowsiness, and lightheadedness. Spironolactone is a potassium-sparing diuretic that will restore normal levels of potassium and prevent the side effects of chlorthalidone. Her slightly advanced age makes it difficult to put her on combination therapy; hence, she shall continue using only two drugs.

Work Cited

Chobanian, Aram V. “Current Use of Diuretics in the Management of Hypertension.” Hypertension 2.4 (2016): 181-182.



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