Similarities between the seven individuals:
The seven deaths are connected due to the similar symptoms they had before dying. The symptoms included:
- Nausea or Vomiting
- Irregular breathing
The electron transport chain:
It is the most significant concluding stage of cellular respiration. The electron transport chain creates a major portion of the ATP. Glycolysis and the Citric Acid Cycle produce the vital antecedents.
Following are some useful facts about the electron transport chain which are helpful in realizing the cause of seven deaths.
- 1 molecule of glucose produces 34 ATP.
- The method consists of a regular electron movement from high to low energy. This creates the proton gradient.
- The proton gradient controls the manufacture of ATP but not the course or movement of electrons.
- The whole process simply takes place when oxygen is accessible.
Another important byproduct of the electron transport chain is water. The reason why oxygen is considered the final electron acceptor is that the electrons are taken up by oxygen molecules to produce water at the final step of the chain. In the absence of oxygen, electrons will escape out into the cells causing all kinds of cellular damage and ultimately killing our cells.
A comprehensive examination of the injured cells presented that mitochondria had very low levels of ATP. Mitochondria produces energy through cellular respiration which got interrupted. Levels of acetyl coenzyme A (CoA) and pyruvate were regular. Glucose and NAD+ levels are low as compared to the normal level while the pyruvate and NADH level is high. These abnormalities influenced the electron transport chain.
Cyanide permanently fixes to cytochrome c oxidase (CcOX) of the electron transport chain and inhibits the transmission of electrons to oxygen which is the final acceptor of electrons. The test carried out for poisoning of all seven patients came positive for cyanide.
Briers, Demarcus. “The Electron Transport Chain Steps Simplified.” DBriers.com, 17 May 2015, www.dbriers.com/tutorials/2012/04/the-electron-transport-chain-simplified/.