The biofilm formation allows collective cell colony or colonies to be highly resistant to the antibiotics (Muzny & Schwebke, 2015). The biofilm formation in infectious diseases can make their treatment hard since they may require a high dose medication for the infection to respond and the infection becomes persistent.
The biofilm formation starts with free-floating microorganism attachment to the surface. It is said that the first biofilm colonist bacteria stick to a surface first by weak and reversible adhesion through hydrophobic effects And Van der Waals Forces (Muzny & Schwebke, 2015). When the colonist are not separated early, they anchor permanently by the use of structures of cell adhesion-like pili. Other bacterial species only attach to the existing colonist because of hydrophobicity.
In bacterial colonization, cell communicates by quorum sensing products like N-acyl homoserine lactone. The moment colonization starts, a biofilm grows by an amalgamation of recruitment and cell division. The polysaccharide matrices enclose the bacterial biofilm. In the last stage of dispersion, the biofilm gets established and changes only in size and shape (Muzny & Schwebke, 2015).
In my view, hand sanitizers though antibacterial, they are not safe, people should always use the old soaps and non-antibacterial ones expect in a situation that they are the only option. The tendency to use hand sanitizer each time one touches doorknobs, elevator button, or the dumbbell, curbs enthusiasm. There are many reasons to always keep off these potential germ killers containing chemical (Wang & Tian, 2015). The main reason is that they often contain triclosan, a substance often considered as an obesogen; a substance that has the potential of causing body weight through disruption of the endocrine system of the body (Wang & Tian, 2015). Reduced exposure to this chemical can aid in prevent his potential chemical that is able to cause weight gain. To reduce the exposure, individual need to use the old soaps that don’t contain any antibacterial component and water where possible. However, in a situation where one cannot reach water and soap, it is safe to use this hand sanitizers or the triclosan-free sanitizers.
Muzny, C. A., & Schwebke, J. R. (2015). Biofilms: an underappreciated mechanism of treatment failure and recurrence in vaginal infections. Clinical Infectious Diseases, 61(4), 601–606.